Huperzine A Review | Brain pill

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Huperzia Huperzine AHuperzine A Review: An effective neurodegenerative treatment

Initial Thoughts

Huperzine A is a supplement made from an extract of a type of firmoss called Huperzia serrata, which is a plant species native to parts of India and southeast Asia. It is used to provide natural but effective relief from cognitive distress.

Huperzine A is an alkaloid compound that stops the creation of acetylcholinesterase. Acetylcholinesterase’s job is to stop an enzyme from breaking down into acetylcholine, which is a learning transmitter. So preventing acetylcholinesterase from doing this allows you to learn more easily.

Huperzine A also is a NMDA receptor antagonist that is able to cross the blood-brain barrier. If you’re unfamiliar with this concept, the blood-brain barrier is a barrier that separates the circulating blood from the brain fluid in the central nervous system. Many compounds are unable to cross this barrier, so it’s impressive that huperzine A can.

Finally, huperzine A is thought to promote the growth of neurites, which are tiny bridges that make connections between brain cells allowing messages to be transmitted. And it also may act as a protectant against neurotoxins and harmful chemicals.

There have been many studies conducted on huperzine A and people have found it to be effective in the treatment of certain neurological conditions such as Alzheimer’s disease. A 2013 study found that huperzine A may be able to improve the cognitive, behavioral and memory function and daily living experience of those with Alzheimer’s disease.

The new horizon is huperzine A being used to improve the mental function and memory making abilities of ordinary adults. While there aren’t any scientific studies that have been able to prove this yet, why not jump on the bandwagon while it’s still early?

Manufacturer and costs

Source Naturals sells huperzine A for the reasonable price of $17.00. The bottle comes with 120 tablets of 200 mcg each. Source Naturals suggests taking two tables a day, so one bottle will last you quite a while.

We also found 50 mcg tablets of huperzine A by the company Vitacost for the very low price of $7.49, just in case you’re interested in starting out at a lower dose, or spacing out your doses throughout the day. Overall, most huperzine A tablets seem to be pretty reasonably priced.

The company LifeMode sells huperzine A as a concentrated extract for $71.88 (USD). It was unclear whether it comes as a powder or tincture, but LifeMode guarantees its pureness and potency. All reviews of this product were positive, although a few did mention how difficult it was to properly measure one dose because one dose is so small.

Pro’s and Con’s


  • Huperzine A is a natural extract that has been studied pretty thoroughly by those in the scientific community.
  • With the various options of huperzine A products, you can easily tailor your own huperzine A schedule and take a lower dose more often during the day.


  • Huperzine A may cause you an upset stomach, so start taking huperzine A slowly and see how you react.
  • If huperzine A is mixed with any other supplement, it may reduce their effectiveness, so be cautious and do your research before mixing huperzine A with other compounds.


Overall, we were pretty impressed with all of the scientific research and medical studies that have been done on huperzine A. We liked how there are different dosage amounts online, so we can pick and choose our daily dose. Finally, we liked how there were few side effects with taking huperzine A.

Total Score: (4 / 5)
Effectiveness: (3 / 5)
Ingredients: (4 / 5)
Side Effects: (4 / 5)
Value for the Money: (4 / 5)

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