Picamilon Review | Brain Pill ReviewsBrainPillReviews.com

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picamilonPicamilon: The secret to stress relief

Initial Thoughts

Our first thoughts regarding picamilon were ones of curiosity. We were impressed with the claims that picamilon can provide a more powerful memory, decreased stress and elevated levels of energy and mood. However, during our initial research, it was revealed that picamilon is not approved for consumption in the US, but is considered a prescription drug in Russia. Why a seemingly powerful and effective supplement would be considered therapeutic in one country but illegal in another was beyond us, so we decided to do some more research.

Picamilon was first developed in the Soviet Union in 1969 by the All-Union Vitamins Scientific Research Institute. Picamilon is a synthetic combination of niacin and GABA. Niacin, otherwise known as B3, is an organic water-soluble compound that is an essential human nutrient, meaning humans cannot survive without it. It is found in a variety of foods including beef, fish, peanuts, legumes, and certain cereals. Meanwhile GABA is a neurotransmitter that inhibits neuronal excitability throughout the nervous system.

The combination of the two is called picamilon, which due to the niacin is able to cross the blood-brain barrier. If you’re unfamiliar with this concept, the blood-brain barrier is a barrier that separates blood from the brain fluid in the central nervous system. Once picamilon crosses the blood-brain barrier, it is hydrolyzed into GABA and niacin. Theoretically, the released GABA is supposed to activate GABA receptors, which then stop the excitability of neurons. This action is known to reduce anxiety and give you a sense of calm. The niacin is known to widen blood vessels and as a result, allow for a greater level of oxygen and nutrient support in the brain. Niacin is also thought to reduce your blood pressure and improving your neural activity, therefore making you feel more relaxed, at ease, and overall in a better mood.

Picamilon’s effects are dose-reliant. So it is better if you experiment with the doses first. Also, if you don’t notice results immediately, keep taking picamilon for at least four to six weeks for you to really notice the effects. If you’re lucky enough to feel a reaction immediately, the short-term effects of a normal dose of about 150 to 300 milligram picamilon last about four to six hours.

Manufacturer and cost

According to the Food and Drug Administration of the United States Picamilon is not considered a dietary ingredient. Therefore, while you were once able to buy picamilon pretty easily, it is now much more difficult.

We were unable to find picamilon sold through Amazon US, although we found picamilon sold in Canada through Absorb Health. One bottle of 100, 100-mgcapsules was $34.00 (USD) and Absorb Health promises money back guarantee. Depending on where you live, you may be able to buy picamilon for cheaper. In Europe is appears you can buy picamilon in bulk form by ordering it from Japan or Belgium. It was quite expensive though, with 5 grams costing $74.00 (USD). We also found a website called i Life Link that appears to sell picamilon and ship it to the US. One bottle has 50, 50-mg capsules and it costs $22.95.

Pro’s and Con’s


  • Picamilon has been scientifically studied for quite some time.
  • You can tailor your daily amount by buying smaller-dose capsules and taking them more often throughout the day.


  • Picamilon might be not approved for consumption in your area, so it may be difficult or expensive to purchase it.
  • You may not notice results immediately, and you may have to take picamilon for a while, which means it may become expensive.


Despite being unapproved for human consumption in the US, we were still impressed with picamilon. We liked how it had been researched and studied by scientists, and we especially liked how we could purchase it in bulk and tailor our daily dose.

Total Score: (3 / 5)
Effectiveness:  (4 / 5)
Ingredients:  (3 / 5)
Side Effects:  (4 / 5)
Value for the Money:  (2 / 5)

Brain Pill Reviews Editors Choice

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